Selected Publications


Last updated: August 25, 2017

Molecular recognition in chemistry and biology

R. K. Castellano, V. Gramlich, F. Diederich, Chem. Eur. J. 2002, 8, 118-129. Rebek imides and their adenine complexes: Preferences for Hoogsteen binding in the solid state and in solution.

E. A. Meyer, R. K. Castellano, F. Diederich, Angew. Chem. Int. Ed. 2003, 42, 1210-1250. Interactions with aromatic rings in chemical and biological recognition.

J. A. Olsen, D. W. Banner, P. Seiler, U. O. Sander, A. D'Arcy, M. Stihle, K. Müller, F. Diederich, Angew. Chem. Int. Ed. 2003, 42, 2507-2511. A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: Evidence for C-F...C=O interactions.

R. Faraoni, M. Blanzat, S. Kubicek, C. Braun, W. B. Schweizer, V. Gramlich, F. Diederich, Org. Biomol. Chem. 2004, 2, 1962-1964. New Rebek imide-type receptors for adenine featuring acetylene-linked pi-stacking platforms.

R. Faraoni, R. K. Castellano, V. Gramlich, F. Diederich, Chem. Commun. 2004, 370-371. H-bonded complexes of adenine with Rebek imide receptors are stabilised by cation-pi interactions and destabilised by stacking with perfluoroaromatics.

F. Hof, D. M. Scofield, W. B. Schweizer, F. Diederich, Angew. Chem. Int. Ed. 2004, 43, 5056-5059. A weak attractive interaction between organic fluorine and an amide group.

R. Paulini, K. Müller, F. Diederich, Angew. Chem. Int. Ed. 2005, 44, 1788-1805. Orthogonal multipolar interactions in structural chemistry and biology.

K. Schärer, M. Morgenthaler, R. Paulini, U. Obst-Sander, D. W. Banner, D. Schlatter, J. Benz, M. Stihle, F. Diederich, Angew. Chem. Int. Ed. 2005, 44, 4400-4404. Quantification of cation-pi interactions in protein-ligand complexes: Crystal-structure analysis of factor Xa bound to a quaternary ammonium ion ligand.

E. Schweizer, A. Hoffmann-Röder, J. A. Olsen, P. Seiler, U. Obst-Sander, B. Wagner, M. Kansy, D. W. Banner, F. Diederich, Org. Biomol. Chem. 2006, 4, 2364-2375. Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors.

E. Schweizer, A. Hoffmann-Röder, K. Schärer, J. Olsen, C. Fäh, P. Seiler, U. Obst-Sander, B. Wagner, M. Kansy, F. Diederich, ChemMedChem 2006, 1, 611-621. A Fluorine scan at the catalytic center of thrombin: C–F, C–OH, and C–OMe Bioisosterism and Fluorine Effects on pKa and log D Values.

A. K. H. Hirsch, F. R. Fischer, F. Diederich, Angew. Chem. Int. Ed. 2007, 46, 338-352. Phosphate recognition in structural biology.

M. Morgenthaler, E. Schweizer, A. Hoffmann-Röder, F. Benini, R. E. Martin, G. Jaeschke, B. Wagner, H. Fischer, S. Bendels, D. Zimmerli, J. Schneider, F. Diederich, M. Kansy, K. Müller, Chemmedchem 2007, 2, 1100-1115. Predicting properties and tuning physicochemical in lead optimization: Amine basicities.

K. Müller, C. Fäh, F. Diederich, Science 2007, 317, 1881-1886. Fluorine in pharmaceuticals: Looking beyond intuition.

F. R. Fischer, W. B. Schweizer, F. Diederich, Angew. Chem. Int. Ed. 2007, 46, 8270-8273. Molecular torsion balances: Evidence for favorable orthogonal dipolar interactions between organic fluorine and amide groups.

Zürcher, M.; Gottschalk, T.; Meyer, S.; Bur, D.; Diederich, F. “Exploring the Flap Pocket of the Antimalarial Target Plasmepsin II: The "55% Rule”, ChemMedChem 2008, 3, 237-240.

Morgenthaler, M.; Aebi, J. D.; Grüninger, F.; Mona, D.; Wagner, B,; Kansy, M.; Diederich, F. ”A Fluorine Scan of Non-Peptidic Inhibitors of Neprilysin: Fluorophobic and Fluorophilic Regions in an Enzyme Active Site”, J. Fluorine Chem. 2008, 129, 852-865.

Zürcher, M.; Diederich, F. “Structure-Based Drug Design: Exploring the Proper Filling of Apolar Pockets at Enzyme Active Sites”, J. Org. Chem. 2008, 73, 4345-4361.

Fischer, F. R.; Wood, P. A.; Allen, F. H.; Diederich, F. “Orthogonal Dipolar Interactions Between Amide Carbonyl Groups”, Proc. Natl. Acad. Sci. U.S.A., 2008, 105, 17290-17294.

Fischer, F. R.; Schweizer W. B.; Diederich, F. “Substituent Effects on the Aromatic Edge-to-Face Interaction”, Chem. Commun. 2008, 4031-4033.

Salonen, L. M.; Bucher, C.; Banner, D. W.; Haap, W.; Mary, J.-L.; Benz, J.; Kuster, O.; Seiler, P.; Schweizer, W. B.; Diederich, F. “Cation- π Interactions at the Active Site of Factor Xa: Dramatic Enhancement Upon Stepwise N-Alkylation of Ammonium Ions”, Angew. Chem. 2009, 121, 825 –828; Angew. Chem. Int. Ed. 2009, 48, 811-814.

Ellermann, M.; Jakob-Roetne, R.; Lerner, C.; Borroni, E.; Schlatter, D.; Roth, D.; Ehler, A.; Rudolph, M.; Diederich, F. “Molecular Recognition at the Active Site of Catechol-O-Methyltransferase (COMT): Energetically Favorable Expulsion of a Water Molecule Imported by a Bisubstrate Inhibitor”, Angew. Chem. Int. Ed. 2009, 48, 9092-9096.

Hardegger, L. A.; Kuhn, B.; Spinnler, B.; Anselm, L.; Ecabert, R.; Stihle, M.; Gsell, B.; Thoma, R.; Diez, J.; Benz, J.; Plancher, J.-M.; Hartmann, G.; Banner, D. W.; Haap, W.; Diederich. F. “Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions”, Angew. Chem. 2011, 123, 329-334; Angew. Chem. Int. Ed. 2011, 50, 314-318.

Salonen, L. M.; Ellermann, M.; Diederich, F. “Aromatic Rings in Chemical and Biological Recognition: Energetics and Structures”, Angew. Chem. 2011, 123, 4908- 4944; Angew. Chem. Int. Ed. 2011, 50, 4808-4842.

L. A. Hardegger, B. Kuhn, B. Spinnler, L. Anselm, R. Ecabert, M. Stihle, B. Gsell, R. Thoma, J. Diez, J. Benz, J.-M. Plancher, G. Hartmann, Y. Isshiki, K. Morikami, N. Shimma, W. Haap, D. W. Banner, F. Diederich, ChemMedChem 2011, 6, 2048-2054. Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments.

M. Ellermann, R. Paulini, R. Jakob-Roetne, C. Lerner, E. Borroni, D. Roth, A. Ehler, W. B. Schweizer, D. Schlatter, M. G. Rudolph, F. Diederich, Chem. Eur. J. 2011, 17, 6369-6381. Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors.

M. C. Witschel, H. W. Höffken, M. Seet, L. Parra, T. Mietzner, F. Thater, R. Niggeweg, F. Röhl, B. Illarionov, F. Rohdich, J. Kaiser, M. Fischer, A. Bacher, F. Diederich, Angew. Chem. Int. Ed. 2011, 50, 7931-7935. Inhibitors of the Herbicidal Target IspD: Allosteric Site Binding.

L. M. Salonen, M. C. Holland, P. S. J. Kaib, W. Haap, J. Benz, J. L. Mary, O. Kuster, W. B. Schweizer, D. W. Banner, F. Diederich, Chem. Eur. J. 2012, 18, 213-222. Molecular Recognition at the Active Site of Factor Xa: Cation-pi Interactions, Stacking on Planar Peptide Surfaces, and Replacement of Structural Water.

L. J. Barandun, F. Immekus, P. C. Kohler, S. Tonazzi, B. Wagner, S. Wendelspiess, T. Ritschel, A. Heine, M. Kansy, G. Klebe, F. Diederich, Chem. Eur. J. 2012, 18, 9246-9257. From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters.

Harder, M.; Kuhn, B.; Diederich, F. “Efficient Stacking on Protein Amide Fragments”, ChemMedChem 2013, 8, 397-404.

Gardarsson, H.; Schweizer, W. B.; Trapp, N.; Diederich, F. "Structuresand Properties of Molecular Torsion Balances to Decipher the Nature of Substituent Effects on the Aromatic Edge-to-Face Interactions", Chem. Eur. J. 2014, 20, 4608-4616.

Dumele, O.; Wu, D.; Trapp, N.; Goroff, N.; Diederich, F. "Halogen Bonding of (Iodoethynyl)benzene Derivatives in Solution", Org. Lett. 2014, 16, 4722-4725.

Fankhauser, D.; Kolarski, D.; Gruening, W. R.; Diederich, F. "Resorcin[4]arene-Based Molecular Baskets and Water-Soluble Container Molecules:  Synthesis and 1H NMR Host-Guest Complexation Studies, Eur. J. Org. Chem. 2014, 3575-3583.

Harder, M.; Carnero Corrales, M. A.; Trapp, N.; Kuhn, B.; Diederich, F. "Rebek Imide Platforms as Model Systems for the Investigation of Weak Intermolecular Interactions", Chem. Eur. J. 2015, 21, 8455-8463.

Persch, E.; Dumele, O.; Diederich, F. "Molecular Recognition in Chemical and Biological Systems", Angew. Chem. 2015, 126, 3343-3382; Angew. Chem. Int. Ed. 2015, 53, 3290-3327.

Dumele, O.; Trapp, N.; Diederich, F. "Halogen Bonding Molecular Capsules", Angew. Chem. 2015, 127, 12516-12521; Angew. Chem. Int. Ed. 2015, 54, 12339-12344.

Gropp, C.; Trapp, N.; Diederich, F.; Angew. Chem. Int. Ed. 2016, 55, 14444-14449; Angew. Chem. 2016, 128, 14659-14664. Alleno-Acetylenic Cage (AAC) Receptors – Chiroptical Switching and Enantioselective Complexation of trans-Dimethylcyclohexane in a Diaxial Conformation.

Alberti, M. N.; Polyhach, Y.; Tzirakis, M. D.; Tödtli, L.; Jeschke, G.; Diederich, F.; Chem. Eur. J. 2016, 22, 10194-10202. Exploring the Strength of the H-Bond in Synthetic Models for Heme Proteins: The Importance of the N–H Acidity of the Distal Base.

Dumele, O; Schreib, B.; Warzok, U.; Trapp, N.; Schalley, C. A.; Diederich, F.; Angew. Chem. Int. Ed. 2017, 56, 1152-1157; Angew. Chem. 2017, 128, 1172-1177. Halogen-Bonded Supramolecular Capsules in the Solid State, in Solution, and in the Gas Phase.

Riwar, L.-J., Trapp, N.; Kuhn, B.; Diederich, F.; Angew. Chem. Int. Ed. 2017, DOI: 10.1002/anie.201703744; Angew. Chem. 2017, DOI: 10.1002/ange.201703744. Substituent Effects in Parallel-Displaced π-π Stacking Interactions: Distance Matters.

Schwab, A.; Illarionov, B.; Frank, A.; Kunfermann, A.; Seet, M.; Bacher, A.; Witschel, M.; Fischer, M.; Groll, M.; Diederich, F.; ACS Chem. Biol., DOI: 10.1021/acschembio 7b00004. Mechanism of Allosteric Inhibition of the Enzyme IspD by Three Different Classes of Ligands.

 

Modern Medicinal Chemistry

C. Lerner, A. Ruf, V. Gramlich, B. Masjost, G. Zürcher, R. Jakob-Roetne, E. Borroni, F. Diederich, Angew. Chem. Int. Ed. 2001, 40, 4040-4042. X-ray crystal structure of a bisubstrate inhibitor bound to the enzyme catechol-O-methyltransferase: A dramatic effect of inhibitor preorganization on binding affinity.

D. A. Carcache, S. R. Hortner, A. Bertogg, C. Binkert, D. Bur, H. P. Marki, A. Dorn, F. Diederich, Chembiochem 2002, 3, 1137-1141. De novo design, synthesis, and in vitro evaluation of a new class of nonpeptidic inhibitors of the malarial enzyme plasmepsin II.

E. A. Meyer, R. Brenk, R. K. Castellano, M. Furler, G. Klebe, F. Diederich, Chembiochem 2002, 3, 250-253. De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: A dramatic sulfur effect on binding affinity.

D. A. Carcache, S. R. Hörtner, P. Seiler, F. Diederich, A. Dorn, H. P. Märki, C. Binkert, D. Bur, Helv. Chim. Acta 2003, 86, 2173-2191. Development of a new class of inhibitors for the malarial aspartic protease plasmepsin II based on a central 7-azabicyclo[2.2.1]heptane scaffold.

D. A. Carcache, S. R. Hörtner, A. Bertogg, F. Diederich, A. Dorn, H. P. Märki, C. Binkert, D. Bur, Helv. Chim. Acta 2003, 86, 2192-2209. A new class of inhibitors for the malarial aspartic protease plasmepsin II based on a central 11-azatricyclo[6.2.1.02,7] undeca-2,4,6-triene scaffold.

C. Lerner, R. Siegrist, E. Schweizer, F. Diederich, V. Gramlich, R. Jakob-Roetne, G. Zürcher, E. Borroni, Helv. Chim. Acta 2003, 86, 1045-1062. Bisubstrate inhibitors for the enzyme catechol O-methyltransferase (COMT): Dramatic effects of ribose modifications on binding affinity and binding mode.

C. Lerner, B. Masjost, A. Ruf, V. Gramlich, R. Jakob-Roetne, G. Zürcher, E. Borroni, F. Diederich, Org. Biomol. Chem. 2003, 1, 42-49. Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity.

F. Hof, F. Diederich, Chem. Commun. 2004, 477-480. Medicinal chemistry in academia: molecular recognition with biological receptors.

R. Paulini, C. Lerner, R. Jakob-Roetne, G. Zürcher, E. Borroni, F. Diederich, Chembiochem 2004, 5, 1270-1274. Bisubstrate inhibitors of the enzyme catechol O-methyltransferase (COMT): Efficient inhibition despite the lack of a nitro group.

K. Schärer, M. Morgenthaler, P. Seiler, F. Diederich, D. W. Banner, T. Tschopp, U. Obst-Sander, Helv. Chim. Acta 2004, 87, 2517-2538. Enantiomerically pure thrombin inhibitors for exploring the molecular recognition features of the oxyanion hole.

C. M. Crane, J. Kaiser, N. L. Ramsden, S. Lauw, F. Rohdich, W. Eisenreich, W. N. Hunter, A. Bacher, F. Diederich, Angew. Chem. Int. Ed. 2006, 45, 1069-1074. Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy.

F. Hof, A. Schütz, C. Fäh, S. Meyer, D. Bur, J. Liu, D. E. Goldberg, F. Diederich, Angew. Chem. Int. Ed. 2006, 45, 2138-2141. Starving the malaria parasite: Inhibitors active against the aspartic proteases plasmepsins I, II, and IV.

E. A. Meyer, N. Donati, M. Guillot, W. B. Schweizer, F. Diederich, B. Steng, R. Brenk, K. Renter, G. Klebe, Helv. Chim. Acta 2006, 89, 573-597. Synthesis, biological evaluation, and crystallographic studies of extended guanine-based (lin-benzoguanine) inhibitors for tRNA-Guanine transglycosylase (TGT).

A. K. H. Hirsch, S. Lauw, P. Gersbach, W. B. Schweizer, F. Rohdich, W. Eisenreich, A. Bacher, F. Diederich, Chemmedchem 2007, 2, 806-810. Nonphosphate inhibitors of IspE protein, a kinase in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antirnalarial therapy.

M. Zürcher, T. Gottschalk, S. Meyer, D. Bur, F. Diederich, Chemmedchem, 2008, 73, 4345-4361. Exploring the Flap Pocket of the Antimalarial Target Plasmepsin II: The 55% Rule Applied to Enzymes.

S. R. Hörtner, T. Ritschel, B. Stengl, C. Kramer, W. B. Schweizer, B. Wagner, M. Kansy, G. Klebe, F. Diederich, Angew. Chem. Int. Ed. 2007, 46, 8266-8269. Potent inhibitors of tRNA-Guanine transglycosylase, an enzyme linked to the pathogenicity of the shigella bacterium: Charg-assisted hydrogen bonding.

Hirsch, A. H. K.; Alphey, M. S.; Lauw, S.; Seet, M.; Barandun, L.; Eisenreich, W.; Rohdich, F.; Hunter, W. N.; Bacher, A.; Diederich, F. “Inhibitors of the Kinase IspE: Structure–Activity Relationships and Co-Crystal Structure Analysis”, Org. Biomol. Chem. 2008, 6, 2719-2730.

Stump, B.; Kaiser, M.; Brun, R.; Krauth-Siegel, R. L.; Diederich, F. “Diaryl Sulfide-Based Inhibitors of Trypanothione Reductase: Inhibition Potency, Revised Binding Mode and Antiprotozoal Activities”, Org. Biomol. Chem., 2008, 6, 3935-3947.

Zürcher, M.; Gottschalk, T.; Meyer, S.; Bur, D.; Diederich, F. “Exploring the Flap Pocket of the Antimalarial Target Plasmepsin II: The "55% Rule”, ChemMedChem 2008, 3, 237-240.

Stump, B.; Eberle, C.; Schweizer, W. B.; Kaiser, M.; Brun, R.; Krauth-Siegel, R. L.; Lentz, D.; Diederich, F. “Pentarfluorosulfanyl as a novel building block for enzyme inhibitors: trypanothione reductase inhibition and antriprotozoal activities of diarylamines“, ChemBioChem 2009, 10, 79-83.

Zürcher, M.; Hof, F.; Barandun, L.; Schütz, A.; Schweizer, W. B.; Meyer, S.; Bur, D.; Diederich, F. “Synthesis of Exo-3-Amino-7-azabicyclo[2.2.1]heptanes as a Class of Malarial Aspartic Protease Inhibitors: Exploration of Two Binding Pockets”, Eur. J. Org. Chem. 2009, 1707-1719.

Fäh, C.; Hardegger, L. A.; Baitsch, L.; Schweizer, W. B.; Meyer, S.; Bur, D.;  Diederich, F. “New Organofluorine Building Blocks:  Inhibition of the Malarial Aspartic Proteases Plasmepsin II and IV by Alicyclic α,α-Difluoroketone Hydrates”, Org. Biomol. Chem. 2009, 7, 3947-3957.

Kohler, P. C.; Ritschel, T.; Schweizer, W. B.; Klebe, G.; Diederich, F., “High-Affinity Inhibitors of tRNA–Guanine Transglycosylase Replacing the Function of a Structural Water Cluster”, Chem. Eur. J., 2009, 15, 10809-10817.

Eberle, C.; Lauber, B. S.; Fankhauser, D.; Kaiser, M.; Brun, R.; Krauth-Siegel, R. L.; Diederich, F. “Improved Inhibitors of Trypanothione Reductase by Combination of Motifs: Synthesis, Inhibition, Potency, Binding Mode, and Antiprotozoal Activity”, ChemMedChem 2011, 6, 292-301.

Ehmke, V.; Heindl, C.; Rottmann, M.; Freymond, C.; Schweizer, W. B.; Brun, R.; Stich, A., Schirmeister, T.; Diederich, F. “Potent and Selective Inhibition of Cysteine Proteases from Plasmodium falciparum and Trypanosoma brucei”, ChemMedChem 2011, 6, 273-278.

P. Mombelli, M. C. Witschel, A. W. van Zijl, J. G. Geist, M. Rottmann, C. Freymond, F. Röhl, M. Kaiser, V. Illarionova, M. Fischer, I. Siepe, W. B. Schweizer, R. Brun, F. Diederich, ChemMedChem 2012, 7, 151-158. Identification of 1,3-Diiminoisoindoline Carbohydrazides as Potential Antimalarial Candidates.

V. Ehmke, J. E. Quinsaat, P. Rivera-Fuentes, C. Heindl, K. Cui, J. Huang, T. Schirmeister, F. Diederich, Org. Biomol. Chem.2012, 10, 5764-5768. Tuning and Predicting Biological Affinity: Aryl Nitriles as Cysteine Protease Inhibitors.

Aureggi, V.; Ehmke, V.; Wieland, J.; Schweizer, W. B.; Bernet, B.; Bur, D. Meyer, S.; Breit, B.; Diederich, F. "Potent Inhibitors of Malarial Aspartic Proteases, the Plasmepsins, by Hydroformylation of Substituted 7-Azanorbornenes", Chem. Eur. J. 2013, 19, 155-164.

Immekus, F.; Barandun, L. J.; Betz, M.; Debaene, F.; Petiot, S.; Sanglier-Cianferani, S.; Reuter, K.; Diederich, F.; Klebe, G. "Launching Spiking Ligands into a Protein-Protein Interface: A Promising Strategy to Destabilize and Break Interface Formation in a tRNA Modifying Enzyme", ACS Chem. Biol. 2013, 8, 1163-1178.

Ehmke, V.; Winkler, E.; Banner, D. W.; Haap, W.; Schweizer, W. B.; Rottmann, M.; Kaiser, M.; Freymond, C.; Schirmeister, T.; Diederich, F. "Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-ray Crystal Structure Analysis with Human Cathepsin L", ChemMedChem 2013, 8, 967-975.

Barandun, L. J.; Immekus, F.; Kohler, P. C.; Ritschel, T.; Heine, A.; Orlando, P.; Klebe, G.; Diederich, F. "High-Affinity Inhibitors of Zymomonas mobilis tRNA-Guanine Transglycosylase through Convergent Optimization", Acta Cryst. 2013, D69, 1798 -1807.

Kunfermann, A.; Witschel, M.; Illarionov, B.; Martin, R.; Rottmann, M.; Höffken, W.; Seet, M.;  Eisenreich, W.; Knölker, H.-J.; Fischer, M.; Bacher, A.; Groll, M.; Diederich, F. "Pseudilins: Halogenated, Allosteric Inhibitors of the Non-Mevalonate Pathway Enzyme Isp", Angew. Chem. 2014, 126, 2267-2272; Angew. Chem. Int. Ed. 2014, 53, 2240-2244.

Neeb, M.; Czodrowski, P.; Heine, A.; Barandun, L. J. Hohn, C.; Diederich, F. Klebe, G. "Chasing Protons: How ITC, Mutagenesis, and pKa Calculations Trace the Locus of Charge in Ligand Binding to a tRNA-binding Enzyme", J. Med. Chem. 2014, 57, 5554-5565.

Neeb, M.; Betz, M.; Heine, A.; Barandun, L. J.; Hohn, C.; Diederich, F.; Klebe, G. "Beyond Affinity: Enthalpy-Entropy Factorization Unravels Complexity of a Flat Structure-Activity Relationship for Inhibition of a tRNA-Modifying Enzyme, J. Med. Chem. 2014, 57, 5566-5578.

Persch, E.; Bryson, S.; Todoroff, N. K.; Eberle, C.; Thelemann, J.; Dirdjaja, N.; Kaiser, M.; Weber, M.; Derbani, H.; Brun, R.; Schneider, G.; Pai, E. F.; Krauth-Siegel, R. L.; Diederich, F., "Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase", ChemMedChem, 2014, 9, 1880-1891.

Barandun, L. J.; Ehrmann, F. R.; Zimmerli, D.; Immekus, F.; Giroud, M.; Grünenfelder, C.; Schweizer, W.B.; Bernet, B.; Betz, M.; Heine, A.; Klebe, G.; Diederich, F. "Replacement of Water Molecules in a Phosphate Binding Site by Furanoside-Appended lin-Benzoguanine Ligands of tRNA-Guanine Transglycosylase (TGT)", Chem. Eur. J. 2015, 21, 126-135.

Witschel, M. C.; Rottmann, R.; Schwab, A.; Leartsakulpanich, U.; Chitnumsub, P.; Seet, M.; Tonazzi, S.; Schwertz, G.; Stelzer, F.; Mietzner, T.; McNamara, C.; Thater, T:; Freymond, C.; Jaruwat, A.; Pinthong, C.; Riangrungroj, P.; Oufir, M.; Hamburger, M.; Mäser, P.; Sanz, L. M.; Charman, S.; Wittlin, S. Yuthavong, Y.; Chaiyen, P.; Diederich, F. "Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT): Co-Crystal Structures of Pyrazolopyrans with Potent Blood and Liver-State Activities", J. Med. Chem. 2015, 58, 3117-3130.

Thelemann, J.; Illarionov, B.; Barylyuk, K.; Geist, J.; Kirchmair, J.; Schneider, P.; Anthore, L.; Root K.; Trapp, N.; Bacher, A.; Witschel, M.; Zenobi, R. Fischer, M.; Schneider, G.; Diederich, F. "Aryl Bis-Sulfonamide Inhibitors of IspF from Arabidopsis thaliana and Plasmodium falciparum", ChemMedChem 2015, 10, 2090-2098.

Lauber, B. S.; Hardegger, L. A.; Asraful, A. K.; Lund, B. A.; Dumele, A.: Harder, M.; Kuhn, B.; Engh, R. A.; Diederich, F. "Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of PKA and a PKB Mimic", Chem. Eur. J. 2016, 22, 211-221.

Hohn, C.; Härtsch, A.; Ehrmann, F. R.; Pfaffeneder, T.; Trapp, N.; Dumele, O.; Klebe, G.; Diederich, F. "An Immucillin-based Transition State-Analogous Inhibitor of tRNA-Guanine Transglycosylase (TGT)", Chem. Eur. J. 2016, 22, 6750-6754.

Giroud, M.; Harder, M.; Kuhn, B.; Haap, W.; Trapp, N.; Schweizer, W. B.; Schirmeister, T.; Diederich, F. "Fluorine Scan of Inhibitors of the Cysteine Protease Human Cathepsin L: Dipolar and Quadrupolar Effects in the π-Stacking of Fluorinated Phenyl Rings on Peptide Amide Bonds", ChemMedChem 2016, 11, 1042-1047.

Neeb, M.; Hohn, C.; Ehrmann, F. R.; Härtsch, A.; Heine, A.; Diederich, D.; Klebe, G. "Occupying a Flat Subpocket in a tRNA-modifying Enzyme with Ordered or Disordered Side Chains: Favorable or Unfavorable for Binding", Bioorg. Med. Chem. 2016, 24, 4900-4910.

Schwertz, G.; Witschel, M.; Rottmann, M.; Bonnert R.; Leartsakulpanich, U.; Chitnumsub, P.; Jaruwat, A.; Ittarat, W.; Schäfer, A.; Aponte, R.; Charman, S.; White, L.; Kundu, A.; Sadhukhan, S.; Lloyd, M.; Freiberg, G.; Srikurmaran, M.; Siggel, M.; Zwyssig, A.; Chaiyen, P.; Diederich, F. "Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with In Vivo Efficavy and Analysis of their Binding Mode", J. Med. Chem. 2017, 60, 4840-4860.

Kuhn, B.; Tichý, M.; Wang, L.; Robinson, S.; Martin, R.; Kuglstatter, A.; Benz, J.; Giroud, M.; Schirmeister, T.; Abel, R.; Diederich, F.; Hert, J. "Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors", J. Med. Chem. 2017, 60, 2485-2497.

Ehrmann, F.; Stojko, J.; Metz, A.; Debaene, F.; Barandun, L.; Heine, A.; Diederich, F.; Cianférani, S.; Reuter, K.; Klebe, G. "Soaking versus Co-Crystallization: Only the Latter Discloses Major Interface Rearrangements of a Homodimericn tRNA-Binding Protein upon Ligand Binding", PLOS ONE, 2017, https://doi.org/10.1371/journal.pone.0175723.

Ehrmann, F.; Stojko, J.; Metz, A.; Debaene, F.; Barandun, L.; Heine, A.; Diederich, F.; Cianférani, S.; Reuter, K.; Klebe, G. "Soaking versus Co-Crystallization: Only the Latter Discloses Major Interface Rearrangements of a Homodimericn tRNA-Binding Protein upon Ligand Binding", PLOS ONE, 2017, https://doi.org/10.1371/journal.pone.0175723.

Giroud, M.; Ivkovic, J.; Martignoni, M.; Fleuti, M.; Trapp, N.; Haap, W.; Kuglstatter, A.; Benz, J.; Kuhn, B.; Schirmeister, T.; Diederich, F. "Inhibition of the Cysteine Protease Human Cathepsin L by Triazine Nitriles: Amide...Heteroarene π-Stacking Interactions and Chalcogen Bonding in the S3 Pocket", ChemMedChem 2017, 12, 257-270.

 

Supramolecular nanosystems


P. J. Skinner, A. G. Cheetham, A. Beeby, V. Gramlich, F. Diederich, Helv. Chim. Acta 2001, 84, 2146-2153. Conformational switching of resorcin[4]arene cavitands by protonation - Preliminary communication.

Y. Yamakoshi, R. R. Schlittler, J. K. Gimzewski, F. Diederich, J. Mater. Chem. 2001, 11, 2895-2897. Synthesis of molecular-gripper-type dynamic receptors and STM-imaging of self-assembled monolayers on gold.

D. Bonifazi, F. Diederich, Chem. Commun. 2002, 2178-2179. Strong intramolecular chromophore interactions in novel bis([60]fullerene)-oligoporphyrin nanoarrays.

D. Bonifazi, A. Salomon, O. Enger, F. Diederich, D. Cahen, Adv. Mater. 2002, 14, 802-805. Tuning electronic properties of semiconductors by adsorption of [60]fullerene carboxylic acid derivatives.

F. Diederich, B. Felber, Proc. Natl. Acad. Sci. USA 2002, 99, 4778-4781. Supramolecular chemistry of dendrimers with functional cores.

D. Latassa, O. Enger, C. Thilgen, T. Habicher, H. Offermanns, F. Diederich, J. Mater. Chem. 2002, 12, 1993-1995. Polysiloxane-supported fullerene derivative as a new heterogeneous sensitiser for the selective photooxidation of sulfides to sulfoxides by 1O2.

N. Papageorgiou, M. Grätzel, O. Enger, D. Bonifazi, F. Diederich, J. Phys. Chem. B 2002, 106, 3813-3822. Lateral electron transport inside a monolayer of derivatized fullerenes anchored on nanocrystalline metal oxide films.

M. J. van Eis, P. Seiler, L. A. Muslinkina, M. Badertscher, E. Pretsch, F. Diederich, R. J. Alvarado, L. Echegoyen, I. Pérez Núñez, Helv. Chim. Acta 2002, 85, 2009-2055. Supramolecular fullerene chemistry: A comprehensive study of cyclophane-type mono- and bis-crown ether conjugates of C70.

P. Weyermann, F. Diederich, J. P. Gisselbrecht, C. Boudon, M. Gross, Helv. Chim. Acta 2002, 85, 571-598. Dendritic iron porphyrins with tethered axial ligands: New model compounds for cytochromes.
P. Weyermann, F. Diederich, Helv. Chim. Acta 2002, 85, 599-617. Dendritic iron porphyrins with a tethered axial ligand as new model compounds for heme monooxygenases.

A. Zingg, B. Felber, V. Gramlich, L. Fu, J. P. Collman, F. Diederich, Helv. Chim. Acta 2002, 85, 333-351. Dendritic iron(II) porphyrins as models for hemoglobin and myoglobin: Specific stabilization of O2 complexes in dendrimers with H-bond donor centers.

V. A. Azov, P. J. Skinner, Y. Yamakoshi, P. Seiler, V. Gramlich, F. Diederich, Helv. Chim. Acta 2003, 86, 3648-3670. Functionalized and partially or differentially bridged resorcin[4]arene cavitands: Synthesis and solid-state structures.

D. Bonifazi, M. Scholl, F. Y. Song, L. Echegoyen, G. Accorsi, N. Armaroli, F. Diederich, Angew. Chem. Int. Ed. 2003, 42, 4966-4970. Exceptional redox and photophysical properties of a triply fused diporphyrin-C60 conjugate: Novel scaffolds for multicharge storage in molecular scale electronics.

B. Felber, C. Calle, P. Seiler, A. Schweiger, F. Diederich, Org. Biomol. Chem. 2003, 1, 1090-1093. Dendritic metalloporphyrins with a distal H-bond donor as mimics of haemoglobin.

D. Joester, M. Losson, R. Pugin, H. Heinzelmann, E. Walter, H. P. Merkle, F. Diederich, Angew. Chem. Int. Ed. 2003, 42, 1486-1490. Amphiphilic dendrimers: Novel self-assembling vectors for efficient gene delivery.

V. A. Azov, B. Jaun, F. Diederich, Helv. Chim. Acta 2004, 87, 449-462. NMR investigations into the vase-kite conformational switching of resorcin[4]arene cavitands.

D. Bonifazi, H. Spillmann, A. Kiebele, M. de Wild, P. Seiler, F. Y. Cheng, H. J. Güntherodt, T. Jung, F. Diederich, Angew. Chem. Int. Ed. 2004, 43, 4759-4763. Supramolecular patterned surfaces driven by cooperative assembly of C60 and porphyrins on metal substrates.

M. Frei, F. Marotti, F. Diederich, Chem. Commun. 2004, 1362-1363. ZnII-induced conformational control of amphiphilic cavitands in Langmuir monolayers.

S. Sergeyev, F. Diederich, Angew. Chem. Int. Ed. 2004, 43, 1738-1740. Regio- and Stereoselective Tether-Directed Remote Functionalization of C60 with Derivatives of the Tröger Base.

N. Armaroli, G. Accorsi, F. Y. Song, A. Palkar, L. Echegoyen, D. Bonifazi, F. Diederich, ChemPhysChem 2005, 6, 732-743. Photophysical and electrochemical properties of meso,meso-linked oligoporphyrin rods with appended fullerene terminals.

V. A. Azov, A. Schlegel, F. Diederich, Angew. Chem. Int. Ed. 2005, 44, 4635-4638. Geometrically precisely defined multinanometer expansion/contraction motions in a resorcin[4]arene cavitand based molecular switch.

D. Bonifazi, G. Accorsi, N. Armaroli, F. Y. Song, A. Palkar, L. Echegoyen, M. Scholl, P. Seiler, B. Jaun, F. Diederich, Helv. Chim. Acta 2005, 88, 1839-1884. Oligoporphyrin arrays conjugated to [60]fullerene: Preparation, NMR analysis, and photophysical and electrochemical properties.

S. Sergeyev, M. Schär, P. Seiler, O. Lukoyanova, L. Echegoyen, F. Diederich, Chem. Eur. J. 2005, 11, 2284-2294. Synthesis of trans-1, trans-2, trans-3, and trans-4 bisadducts of C60 by regio- and stereoselective tether-directed remote functionalization.

V. A. Azov, A. Beeby, M. Cacciarini, A. G. Cheetham, F. Diederich, M. Frei, J. K. Gimzewski, V. Gramlich, B. Hecht, B. Jaun, T. Latychevskaia, A. Lieb, Y. Lill, F. Marotti, A. Schlegel, R. R. Schlittler, P. J. Skinner, P.
Seiler, Y. Yamakoshi, Adv. Funct. Mater. 2006, 16, 147-156. Resorcin[4]arene cavitand-based molecular switches.

F. Y. Cheng, S. Zhang, A. Adronov, L. Echegoyen, F. Diederich, Chem. Eur. J. 2006, 12, 6062-6070. Triply fused Zn(II)-porphyrin oligomers: Synthesis, properties, and supramolecular interactions with single-walled carbon nanotubes (SWNTs).

M. Frei, F. Diederich, R. Tremont, T. Rodriguez, L. Echegoyen, Helv. Chim. Acta 2006, 89, 2040-2057. Tetrathiafulvalene (TTF)-bridged resorcin[4]arene cavitands: Towards new electrochemical molecular switches.

M. Guillot, S. Eisler, K. Weller, H. P. Merkle, J. L. Gallani, F. Diederich, Org. Biomol. Chem. 2006, 4, 766-769. Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers.

P. Roncucci, L. Pirondini, G. Paderni, C. Massera, E. Dalcanale, V. A. Azov, F. Diederich, Chem. Eur. J. 2006, 12, 4775-4784. Conformational Behavior of pyrazine-bridged and mixed-bridged cavitands: A general model for solvent effects on thermal "vase-kite" switching.

H. Spillmann, A. Kiebele, M. Stöhr, T. A. Jung, D. Bonifazi, F. Y. Cheng, F. Diederich, Adv. Mater. 2006, 18, 275. A two-dimensional porphyrin-based porous network featuring communicating cavities for the templated complexation of fullerenes.

W. W. H. Wong, F. Diederich, Chem. Eur. J. 2006, 12, 3463-3471. Regio- and diastereoselective synthesis of bis- and tetrakisadducts of C70 by directed remote functionalization using troger base tethers.

T. Gottschalk, B. Jaun, F. Diederich, Angew. Chem. Int. Ed. 2007, 46, 260-264. Container molecules with portals: Reversibly switchable cycloalkane complexation.

D. Bonifazi, O. Enger, F. Diederich, Chem. Soc. Rev. 2007, 36, 390-414. Supramolecular [60]fullerene chemistry on surfaces.

D. Bonifazi, A. Kiebele, M. Stöhr, F. Y. Cheng, T. Jung, F. Diederich, H. Spillmann, Advanced Functional Materials 2007, 17, 1051-1062. Supramolecular nanostructuring of silver surfaces via self-assembly of [60]fullerene and porphyrin modules.

N. Wintjes, D. Bonifazi, F. Y. Cheng, A. Kiebele, M. Stohr, T. Jung, H. Spillmann, F. Diederich, Angew. Chem. Int. Ed. 2007, 46, 4089-4092. A supramolecular multiposition rotary device.

Gottschalk, T.; Jarowski, P. D.; Diederich, F. “Reversibly Controllable Guest Binding in Precisely Defined Cavities: Selectivity, Induced Fit, and Molecular Switching in Novel Resorcin[4]arene-Based Container Molecules“, Tetrahedron 2008, 64, 8307-8317.

Wintjes, N.; Hornung, J.; Lobo-Checa, J.; Voigt, T.; Samuely, T.; Thilgen, C.; Stöhr, M.; Diederich, F.; Jung, T. A. “Supramolecular Synthons on Surfaces: Controlling Dimensionality and Periodicity of Tetraarylporphyrin Assemblies by the Interplay of Cyano and Alkoxy Substituents”, Chem. Eur. J. 2008, 14, 5794-5802.

Maier, S.; Fendt, L.-A.; Zimmerli, L.; Glatzel, T.; Pfeiffer, O.; Diederich, F.; Meyer E. “Nano-engineering of Molecular Porphyrin Wires on Insulating Surfaces“, Small 2008, 4, 1115-1118.

Dube, H.; Kasumaj, B.; Calle, C.; Saito, M.; Jeschke, G.; Diederich, F. “Direct Evidence for Hydrogen Bonding to Bound Dioxygen in a Myoglobin/Hemoglobin Model System by Pulse EPR Spectroscopy”, Angew. Chem. 2008, 120, 2638-2642; Angew. Chem. Int. Ed. 2008, 47, 2600-2603.

Dube, H.; Kasumay, B.; Calle, C.; Felber, B.; Saito, M.; Jeschke, G.; Diederich, F. “Probing Hydrogen-Bonding to Bound Dioxygen in Synthetic Models for Heme Proteins: The Importance of Precise Geometry” Chem. Eur. J. 2009, 15, 125-135.

Kraszewska, A.; Rivera-Fuentes, P.; Thilgen, C.; Diederich, F. “First Enantiomerically Pure C70-Adducts with a Non-inherently Chiral Addition Pattern ”New J. Chem. 2009, 33, 386-396.    

Kawai, S.; Maier, S.; Glatzel, T.; Koch, S.; Such, B.; Zimmerli, L.; Fendt, L.-A.; Diederich, F.; Meyer, E. “Cutting and self-healing molecular wires studied by Dynamic Force Microscopy”, Appl. Phys.Lett. 2009, 95, 103109-1-103109-3.

Fendt, L.-A.; Stöhr, M.; Wintjes, N.; Enache, M.; Jung, T.; Diederich, F. “Modification of Supramolecular Binding Motifs Induced by Substrate Registry: Formation of Self-Assembled Macrocycles and Chain-Like Patterns”, Chem. Eur. J., in press. 2009, 15, 11139-11150.

Pochorovski, I.; Breiten, B.; Schweizer, W. B.; Diederich, F. “FRET Studies on a Series of BODIPY Dye-Labeled Switchable Resorcin[4]arene Cavitands”, Chem. Eur. J. 2010, 16, 12590-12602.

Fesser, P.; Iacovita, C.; Wäckerlin, C.; Vijayaraghavan, S.; Ballav, N.; Howes, K.; Gisselbrecht, J.-P.; Boudon, C.; Stöhr, M.; Jung, T. A.; Diederich, F. „Visualizing the Product of a Formal Cycloaddition of 7,7,8,8-Tetracyano-p-quinodimethane (TCNQ) to an Acetylene-appended Porphyrin by Scanning Tunneling Microscopy on Au(111), Chem. Eur. J. 2011, 17, 5246-5250.

M. Stöhr, S. Boz, M. Schär, M. T. Nguyen, C. A. Pignedoli, D. Passerone, W. B. Schweizer, C. Thilgen, T. A. Jung, F. Diederich, Angew. Chem. Int. Ed. 2011, 50, 9982-9986. Self-Assembly and Two-Dimensional Spontaneous Resolution of Cyano-Functionalized [7]Helicenes on Cu(111).

J. Hornung, D. Fankhauser, L. D. Shirtcliff, A. Praetorius, W. B. Schweizer, F. Diederich, Chem. Eur. J. 2011, 17, 12362-12371. Cycloalkane and Alicyclic Heterocycle Complexation by New Switchable Resorcin[4] arene-Based Container Molecules: NMR and ITC Binding Studies.

I. Pochorovski, C. Boudon, J.-P. Gisselbrecht, M.-O. Ebert, W. B. Schweizer, F. Diederich, Angew. Chem. Int. Ed. 2012, 51, 262-266. Quinone-Based, Redox-Active Resorcin[4]arene Cavitands.

Pochorovski, I.; Ebert, M.-O.; Gisselbrecht, J.-P.; Boudon, C.; Schweizer, W. B.; Diederich, F. „Redox-Switchable Resorcin[4]arene Cavitands: Molecular Grippers”, J. Am. Chem. Soc. 2012, 134, 14702-14705.

Iacovita, C.; Fesser, P.; Vijayaraghavan, S.; Enache, M.; Stöhr, M.; Diederich, F.; Jung, T. A. „Controlling the Dimensionality and Structure of Supramolecular Porphyrin Assemblies by their Functional Substituents: Dimers, Chains, and Close Packed 2D Assemblies“, Chem. Eur. J. 2012, 18, 14610-14613.

Pochorovski, I.; Knehans, T.; Nettels, D.; Mueller, A.; Schweizer, W. B.;   Caflisch, A; Schuler, B.; Diederich, F. "Experimental and Computational Study of BODIPY Dye-Labeled Cavitand Dynamics", J. Am. Chem. Soc. 2014, 136, 2441-2449.

Pochorovski, I.; Milić, J.; Kolarski, D.; Gropp, C.; Schweizer, B.; Diederich, F. "Evaluation of Hydrogen-Bond Acceptors for Redox-Switchable Resorcin[4]arene Cavitands", J. Am. Chem. Soc. 2014, 136, 3852-3858.

Schweinfurth, D.; Zalibera, M.; Kathan, M..; Shen, C.; Mazzolini, M.; Trapp, N.; Crassous, J.; Gescheidt, G.; Diederich, F. "Helicene Quinones: Redox-Triggered Chiroptical Switching and Chiral Recognition of the Semiquinone Radical Anion Lithium Salt by ENDOR Spectroscopy", J. Am. Chem. Soc. 2014, 136, 13045-13052.

Tzirakis, M. D.; Alberti, M. N.; Weissman, H.; Rybtchinski, B.; Diederich, F. "Enantiopure Laterally-Functionalized Alleno-Acetylenic Macrocycles: Synthesis, Chiroptical Properties, and Self-Assembly in Aqueous Media", Chem. Eur. J. 2014, 20, 16070-16073.

Gidron, O.; Ebert, M.-O.; Trapp, N.; Diederich, F. "Chiroptical Detection of Non-Chromophoric, Achiral Guests by Enantiopure Alleno-Acetylenic Helicages", Angew. Chem. 2014, 126, 13833-13837; Angew. Chem. Int. Ed. 2014, 53, 13614-13618.

Gidron, O.; Jirásek, M.; Trapp, N.; Ebert, M.-O.; Zhang, X.; Diederich, F. "Homochiral [2]Catenane and Bis[2]catenane from Alleno-Acetylenic Helicates - A Highly Selective Narcissistic Self-Sorting Process", J. Am. Chem. Soc. 2015, 137, 12502-12505.

Alberti, M. N.; Polyhach, Y.; Tzirakis, M. D.; Tödtli, L.; Jeschke, G.; Diederich, F. "Exploring the Strength of the H-Bond in Synthetic Models for Heme Proteins: The Importance of the N–H Acidity of the Distal Base" Chem. Eur. J. 2016, 22, 10194-10202.

Milić, J.; Zalibera, M.; Pochorovski, I.; Trapp, N.; Nomrowski, J.; Neshchadin, D.; Ruhlmann, L.; Boudon, C.; Wenger, O. S.; Savitsky, A.; Lubitz, W.; Gescheidt, G.; Diederich, F. "Paramagnetic Molecular Grippers: The Elements of Six-State Redox Switches", J. Phys. Chem. Lett. 2016, 7, 2470-2477.

 

Carbon-rich Materials

S. W. McElvany, M. M. Ross, N. S. Goroff, F. Diederich, Science (Washington) 1993, 259, 1594-1596. Cyclocarbon coalescence - mechanisms for tailor-made fullerene formation.

J. Anthony, A. M. Boldi, Y. Rubin, M. Hobi, V. Gramlich, C. B. Knobler, P. Seiler, F. Diederich, Helv. Chim. Acta 1995, 78, 13-45. Tetraethynylethenes - fully cross-conjugated pi-electron chromophores and molecular scaffolds for all-carbon networks and carbon-rich nanomaterials.

R. E. Martin, F. Diederich, Angew. Chem. Int. Ed. 1999, 38, 1350-1377. Linear monodisperse pi-conjugated oligomers: model compounds for polymers and more.

P. Siemsen, R. C. Livingston, F. Diederich, Angew. Chem. Int. Ed. 2000, 39, 2633-2657. Acetylenic coupling: A powerful tool in molecular construction.

F. Diederich, Chem. Commun. 2001, 219-227. Carbon-rich acetylenic scaffolding: rods, rings and switches.

L. Gobbi, P. Seiler, F. Diederich, V. Gramlich, C. Boudon, J. P. Gisselbrecht, M. Gross, Helv. Chim. Acta 2001, 84, 743-777. Photoswitchable tetraethynylethene-dihydroazulene chromophores.

R. C. Livingston, L. R. Cox, V. Gramlich, F. Diederich, Angew. Chem. Int. Ed. 2001, 40, 2334. 1,3-diethynylallenes : New modules for three-dimensional acetylenic scaffolding.

M. B. Nielsen, M. Schreiber, Y. G. Baek, P. Seiler, S. Lecomte, C. Boudon, R. R. Tykwinski, J. P. Gisselbrecht, V. Gramlich, P. J. Skinner, C. Bosshard, P. Gunter, M. Gross, F. Diederich, Chem. Eur. J. 2001, 7, 3263-3280. Highly functionalized dimeric tetraethynylethenes and expanded radialenes: Strong evidence for macrocyclic cross-conjugation.

P. Manini, W. Amrein, V. Gramlich, F. Diederich, Angew. Chem. Int. Ed. 2002, 41, 4339-4343. Expanded cubane: Synthesis of a cage compound with a C56 core by acetylenic scaffolding and gas-phase transformations into fullerenes.

F. Mitzel, C. Boudon, J. P. Gisselbrecht, M. Gross, F. Diederich, Chem. Commun. 2002, 2318-2319. pi-electron conjugation effects in antiaromatic dehydro[12] - and aromatic dehydro[18]-annulenes.

N. N. P. Moonen, C. Boudon, J. P. Gisselbrecht, P. Seiler, M. Gross, F. Diederich, Angew. Chem. Int. Ed. 2002, 41, 3044-3047. Cyanoethynylethenes: A class of powerful electron acceptors for molecular scaffolding.

F. Denonne, P. Seiler, F. Diederich, Helv. Chim. Acta 2003, 86, 3096-3117. Towards the synthesis of azoacetylenes.

C. Lepetit, M. B. Nielsen, F. Diederich, R. Chauvin, Chem. Eur. J. 2003, 9, 5056-5066. Aromaticity and Electron Affinity of carbok-[3]radialenes, k = 0, 1, 2.

F. Mitzel, C. Boudon, J. P. Gisselbrecht, P. Seiler, M. Gross, F. Diederich, Chem. Commun. 2003, 1634-1635. Donor-substituted peralkynylated "radiaannulenes": novel all-carbon macrocycles with an intense intramolecular charge- transfer.

N. N. P. Moonen, R. Gist, C. Boudon, J. P. Gisselbrecht, P. Seiler, T. Kawai, A. Kishioka, M. Gross, M. Irie, F. Diederich, Org. Biomol. Chem. 2003, 1, 2032-2034. Donor-substituted cyanoethynylethenes: powerful chromophores for opto-electronic applications.

A. Auffrant, B. Jaun, P. D. Jarowski, K. N. Houk, F. O. Diederich, Chem. Eur. J. 2004, 10, 2906-2911. Peralkynylated buta-1,2,3-trienes: Exceptionally low rotational barriers of cumulenic C=C bonds in the range of those of peptide C-N bonds.

J. P. Gisselbrecht, N. N. P. Moonen, C. Boudon, M. B. Nielsen, F. Diederich, M. Gross, Eur. J. Org. Chem. 2004, 2959-2972. Redox properties of linear and cyclic scaffolds based on di- and tetraethynylethene.

F. Mitzel, C. Boudon, J. P. Gisselbrecht, P. Seiler, M. Gross, F. Diederich, Helv. Chim. Acta 2004, 87, 1130-1157. Donor-substituted perethynylated dehydroannulenes and radiaannulenes: Acetylenic carbon sheets featuring intense intramolecular charge transfer.

N. N. P. Moonen, F. Diederich, Org. Biomol. Chem. 2004, 2, 2263-2266. Limitations on the use of UV/Vis spectroscopy for the evaluation of conjugation effectiveness.

J. M. Raimundo, S. Lecomte, M. J. Edelmann, S. Concilio, I. Biaggio, C. Bosshard, P. Günter, F. Diederich, J. Mater. Chem. 2004, 14, 292-295. Synthesis and properties of a ROMP backbone polymer with efficient, laterally appended nonlinear optical chromophores.

N. E. Utesch, F. Diederich, C. Boudon, J. P. Gisselbrecht, M. Gross, Helv. Chim. Acta 2004, 87, 698-718. Solid-phase synthesis of oligo(triacetylene)s and oligo(phenylenetriacetylene)s employing Sonogashira and Cadiot-Chodkiewicz-type cross-coupling reactions.

T. Michinobu, J. C. May, J. H. Lim, C. Boudon, J. P. Gisselbrecht, P. Seiler, M. Gross, I. Biaggio, F. Diederich, Chem. Commun. 2005, 737-739. A new class of organic donor-acceptor molecules with large third-order optical nonlinearities.

N. N. P. Moonen, W. C. Pomerantz, R. Gist, C. Boudon, J. P. Gisselbrecht, T. Kawai, A. Kishioka, M. Gross, M. Irie, F. Diederich, Chem. Eur. J. 2005, 11, 3325-3341. Donor-substituted cyanoethynylethenes: pi- Conjugation and band-gap tuning in strong charge-transfer chromophores.

S. Odermatt, J. L. Alonso-Gomez, P. Seiler, M. M. Cid, F. Diederich, Angew. Chem. Int. Ed. 2005, 44, 5074-5078. Shape-persistent chiral alleno-acetylenic macrocycles and cyclophanes by acetylenic scaffolding with 1,3-diethynylallenes.

A. S. Andersson, K. Kilså, T. Hassenkam, J.-P. Gisselbrecht, C. Boudon, M. Gross, M. B. Nielsen, F. Diederich, Chem. Eur. J. 2006, 12, 8451-8459. Synthesis and characteristics of a non-aggregating tris(tetrathiafulvaleno)dodecadehydro[18]annulene.

M. Kivala, F. Mitzel, C. Boudon, J.-P. Gisselbrecht, P. Seiler, M. Gross, Chem. Asian J. 2006, 1, 479-489. Two-dimensional acetylenic scaffolding: Extended donor-substituted perethynylated dehydroannulenes.

T. Michinobu, C. Boudon, J. P. Gisselbrecht, P. Seiler, B. Frank, N. N. P. Moonen, M. Gross, F. Diederich, Chem. Eur. J. 2006, 12, 1889-1905. Donor-substituted 1,1,4,4-tetracyanobutadienes (TCBDs): New chromophores with efficient intramolecular charge-transfer interactions by atom-economic synthesis.

F. Bures, W. B. Schweizer, J. C. May, C. Boudon, J. P. Gisselbrecht, M. Gross, I. Biaggio, F. Diederich, Chem. Eur. J. 2007, 13, 5378-5387. Property tuning in charge-transfer chromophores by systematic modulation of the spacer between donor and acceptor.

J. C. May, I. Biaggio, F. Bures, F. Diederich, Appl. Phys. Lett. 2007, 90, 251106. Extended conjugation and donor-acceptor substitution to improve the third-order optical nonlinearity of small molecules.

M. Kivala, C. Boudon, J.-P. Gisselbrecht, P. Seiler, M. Gross, F. Diederich, Angew. Chem. Int. Ed. 2007, 46, 6357-6360. Charge-transfer chromophores by cycloaddition-Retro-electrocyclization: Multivalent systems and cascade reactions.

M. Kivala, C. Boudon, J.-P. Gisselbrecht, P. Seiler, M. Gross, F. Diederich, Chem. Commun., 2007,4731-4733. A novel reaction of 7,7,8,8-tetracyanoquinodimethane (TCNQ): charge-transfer chromophores by [2 + 2] cycloaddition with alkynes.

P. Reutenauer, M. Kivala, P. D. Jarowski, C. Boudon, J.-P. Gisselbrecht, M. Gross, F. Diederich, Chem. Commun., 2007, 4898 - 4900. New strong organic acceptors by cycloaddition of TCNE and TCNQ to donor-substituted cyanoalkynes.

Jarowski, P.; Wu, Y.-L.; Schweizer, W. B.; Diederich, F. “1,2,3-Triazoles as Conjugative π-Linkers in Push-Pull Chromophores: Importance of Substituent Positioning on Intramolecular Charge-Transfer”, Org. Lett. 2008, 10, 3347-3350.

Kivala, M.; Stanoeva, T.; Michinobu, T.; Frank, B.; Gescheidt, G.; Diederich, F. “One-Electron Reduced and Oxidized Stages of Donor-Substituted 1,1,4,4-Tetracyanobuta-1,3-dienes of Different Molecular Architectures”, Chem. Eur. J., 2008, 14, 7638-7647.

B. Esembeson, M. L. Scimecam, T. Michinobu, F. Diederich, I. Biaggio, "A High-Opticl Quality Supramolecular Assembly for Third-Order Integrated Nonlinear Optics", Adv. Mater. 2008, 20, 4584-4587.

Kivala, M.; Diederich, F. “Acetylene-Derived Strong Organic Acceptors for Planar and Nonplanar Push-Pull Chromophores”, Acc. Chem. Res. 2009, 42 (2), 235-248.

Jarowski, P. D.; Wu, Y.-L.; Boudon, C.; Gisselbrecht, J.-P.; Schweizer, W. B.; Diederich, F. “New Donor-Acceptor Chromophores by Formal [2+2] Cycloaddition of Donor-Substituted Alkynes to Dicyanovinyl Derivatives”, Org. Biomol. Chem. 2009, 7, 1312-1322.

Koos, C.; Vorreau, P.; Vallaitis, T.; Dumon, P.; Baets, R.; Esembeson, B.; Biaggio, I.; Michinobu, T.; Diederich, F.; Freude. W.; Leuthold. J. “All-Optical High-Speed Signal Processing with Silicon-Organic Hybrid Slot Waveguides”, Nature Photonics, 2009, 3, 216-227.

Kivala, M.; Boudon, C.; Gisselbrecht, J.-P.; Enko, B.; Seiler, P.; Müller, I. B.; Langer, N.; Jarowski, P. D.; Gescheidt, G.; Diederich, F. “Organic Super-Acceptors with Efficient Intramolecular Charge-Transfer Interactions by [2+2] Cycloadditions of TCNE, TCNQ, and F4-TCNQ to Donor-Substituted Cyanoalkynes”, Chem. Eur. J. 2009, 15, 4111-4123.

Alonso-Gómez, J. L.; Rivera-Fuentes, P.; Harada, N.; Berova, N. Diederich, F. “An Enantiomerically Pure Alleno-Acetylenic Macrocycle: Synthesis and Rationalization of Ist Outstanding Chiroptical Response“, Angew. Chem. 2009, 121, 5653-5656; Angew. Chem. Int. Ed. 2009, 48, 5545-5548.

Frank, B. B.; Camafort Blanco, B.; Jakob, S.; Ferroni, F.; Pieraccini, S.; Ferrarini, A.; Boudon, C.; Gisselbrecht, J.-P.; Seiler, P.; Spada, G. P.; Diederich, F. “N-Arylated 3,5-Dihydro-4-dinaphtho[2,1-c:1',2'-e]azepines: Axially Chiral Donors With High Helical Twisting Powers For Non-planar Push-Pull Chromophores”, Chem. Eur. J., 2009, 15, 9005-9016.

Kato, S.; Kivala, M.; Schweizer, W. B.; Boudon, C.; Gisselbrecht, J.P.; Diederich, F.“Origin of Intense Intramolecular Charge-Transfer Interactions in Non-Planar Push-Pull Chromophores”, Chem. Eur. J. 2009, 15, 8687-8691.

Diederich, F.; Kivala, M. “All-Carbon Scaffolds by Rational Design”, Adv. Mater. 2010, 22, 803–812.

Wu, Y.-L.; Jarowski, P. D.; Schweizer, W. B.; Diederich, F. “Mechanistic Investigation of the Dipolar [2+2] Cycloaddition–Cycloreversion Reaction between 4-(N,N-Dimethylamino)phenylacetylene and Arylated 1,1-Dicyanovinyl Derivatives To Form Intramolecular Charge-Transfer Chromophores“, Chem. Eur. J., 2010, 16, 202-211.

Rivera-Fuentes, P.; Alonso-Gómez, J. L.; Petrovic, A. F.; Santoro, F.; Harada, N.; Berova, N.; Diederich, F. “Amplification of Chirality in Mono-disperse, Enantiopure Alleno-Acetylenic Oligomers”, Angew. Chem. 2010, 122, 2296-2300; Angew. Chem. Int. Ed. 2010, 49, 2247-2250.

Yamada, M.; Rivera-Fuentes, P.; Schweizer W. B.; Diederich, F. “Optical Stability of Axially Chiral Push-Pull-Substituted Buta-1,3-dienes Enforced by a Singe Methyl Group on the [60]Fullerene Surface”, Angew. Chem. 2010, 122, 3611 –3615; Angew. Chem. Int. Ed. 2010, 49, 3532-3535.

Kato, S.-i.; Roberts Beels, M. T.; La Porta, P.; Schweizer, W. B.; Boudon, C.; Gisselbrecht, J.-P.; Biaggio, I.; Diederich, F. “Homoconjugated Push–Pull and Spiro Systems: Intramolecular Charge-Transfer Interactions and Third-Order Optical Nonlinearities”, Angew. Chem. 2010, 122, 6343 -6347; Angew. Chem. Int. Ed. 2010, 49, 6207-6211.

Wu, Y.-L.; Bures, F.; Jarowski, P. D.; Schweizer, W. B.; Diederich, F. “Pro-aromaticity: Organic Charge-Transfer Chromophores with Small HOMO-LUMO Gaps“, Chem. Eur. J. 2010, 16, 9592 - 9605.

Rivera-Fuentes, P.; Alonso-Gomez, J. L.; Petrovic, A. G.; Seiler, P.; Santoro, F.; Harada, N.; Berova, N.; Rzepa, H. S.; Diederich, F. “Enantiomerically Pure Alleno-Acetylenic Macrocycles: Synthesis, Solid State Structures, Chiroptical Properties, and Electron Localization Function Analysis”, Chem. Eur. J. 2010, 16, 9796-9807.

Yamada, M.; Schweizer, W. B.; Schoenebeck, F.; Diederich, F. „Unprecedented Thermal Rearrangement of Push-Pull-Chromophore –[60]Fullerene Conjugates: Formation of Chiral 1,2,9,12-Tetrakis-Adducts”, Chem. Commun. 2010, 46, 5334 - 5336.

Rivera-Fuentes, P.; Nieto-Ortega, B.; Schweizer, W. B.; Lopez Navarrete, J. T. L. , Casado, J.; Diederich, F. "Enantiopure, Monodisperse Alleno-acetylenic Cyclooligomers: Effect of Symmetry and Conformational Flexibility on the Chiroptical Properties of Carbon-rich Compounds", Chem. Eur. J. 2011, 17, 3876-3885.

Jayamurugan, G.; Gisselbrecht, J.-P.; Boudon, C.; Schoenebeck, F.; Schweizer, W. B.; Bernet, B.; Diederich, F. "Expanding the chemical space for push-pull chromophores by non-concerted [2+2] and [4+2] cycloadditions: access to a highly functionalised 6,6-dicyanopentafulvene with an intense, low-energy charge-transfer band", Chem. Commun. 2011, 47, 4520-4522.

C. M. Reisinger, P. Rivera-Fuentes, S. Lampart, W. B. Schweizer, F. Diederich, Chem. Eur. J. 2011, 17, 12906-12911. Cascade Pericyclic Reactions of Alleno-Acetylenes: Facile Access to Highly Substituted Cyclobutene, Dendralene, Pentalene, and Indene Skeletons.

M. Chiu, B. Jaun, M. T. R. Beels, I. Biaggio, J.-P. Gisselbrecht, C. Boudon, W. B. Schweizer, M. Kivala, F. Diederich, Org. Lett. 2012, 14, 54-57. N,N'-Dicyanoquinone Diimide-Derived Donor-Acceptor Chromophores: Conformational Analysis and Optoelectronic Properties.

P. Rivera-Fuentes, F. Diederich, Angew. Chem. Int. Ed. 2012, 51, 2818-2828. Allenes in Molecular Materials.

Y.-L. Wu, F. Tancini, W. B. Schweizer, D. Paunescu, C. Boudon, J.-P. Gisselbrecht, P. D. Jarowski, E. Dalcanale, F. Diederich, Chem. Asian J. 2012, 7, 1185-1190. Proacetylenic Reactivity of a Push-Pull Buta-1,2,3-triene: New Chromophores and Supramolecular Systems.

F. Tancini, Y.-L. Wu, W. B. Schweizer, J.-P. Gisselbrecht, C. Boudon, P. D. Jarowski, M. T. Beels, I. Biaggio, F. Diederich, Eur. J. Org. Chem. 2012, 2756-2765. 1,1-Dicyano-4-[4-(diethylamino)phenyl]buta-1,3-dienes: Structure-Property Relationships.

Finke, A. D.; Dumele, O.; Zalibera, M.; Confortin, D.; Cias, P.; Jayamurugan, G.; Gisselbrecht, J.-P.; Boudon, C.; Schweizer, W. B.; Gescheidt, G. "6,6-Dicyanopentafulvenes: Electronic Structure and Regioselectivity in [2+2] Cycloaddition-Retroelectrocyclization Reactions", J. Am. Chem. Soc. 2012, 134, 18139-18146.

Wu, Y.-L.; Stuparu, M.; Boudon, C.; Gisselbrecht, J.-P.; Schweizer, W. B.; Baldridge, K.; Siegel, J.; Diederich, F. “Structural, Optical, and Electrochemical Properties of Three-Dimensional Push-Pull Corannulenes”, J. Org. Chem. 2012, 77, 11014-11026.

Jayamurugan, G.; Dumele, O.; Gisselbrecht, J.-P.; Boudon, C.; Schweizer, W. B.; Bernet, B.; Diederich, F. „Expanding the Chemical Structure Space of Opto-Electronic Molecular Materials: Unprecedented Push–Pull Chromophores by Reaction of a Donor-Substituted Tetracyanofulvene with Electron-Rich Alkynes“, J. Am. Chem. Soc. 2013, 135, 3599-3606.

Tzirakis, M. D.; Marion, N.; Schweizer, W. B.; Diederich, F. "A Shape-Persistent Alleno-Acetylenic Macrocycle with Modifiable Periphery: Synthesis, Chiroptical Properties and H-bond-driven Self-Assembly into a Homochiral Columnar Structure", Chem. Commun. 2013, 49, 7605 -7607.

Finke, A. D.; Haberland, S.; Schweizer, W. B.; Chen, P.; Diederich, F. "A Mild Thermal Pentafulvene-to-Benzene Rearrangement", Angew. Chem. 2013, 125, 10010-10013; Angew. Chem. Int. Ed. 2013, 52, 9827-9830.

Štefko, M.; Tzirakis, M. D.; Breiten, B.; Ebert, M.-O.; Dumele, O.; Schweizer, W. B.; Gisselbrecht, J.-P.; Boudon, C.; Beels, M. T. R.; Biaggio, I.; Diederich, F. "Donor-Acceptor (D–A) Substituted Polyyne Chromophores: Modulation of their Optoelectronic Properties by Varying the Length of the Acetylene Spacer", Chem. Eur. J. 2013, 19, 12693-1270.

Tancini, F.; Monti, F.; Howes, K.; Belbakra, A.; Listorti, A.; Schweizer, W. B.; Reutenauer, P.; Alonso-Gomez, J.-L.; Chiorboli, C.; Urner, L. M.; Gisselbrecht, J-P.; Boudon, C.; Armaroli, N.; Diederich, F. "Cyanobuta-1,3-dienes as Novel Electron Acceptors for Photoactive Multicomponent Systems", Chem. Eur. J. 2014, 20, 202-216.

Dengiz, C.; Dumele, O.; Kato, S-I.; Zalibera, M.; Cias, P.; Schweizer, W. B.; Boudon, C.; Gisselbrecht, J.-P.; Gescheidt, G.; Diederich, F. "From Homoconjugated Push-Pull Chromophores to Donor-Acceptor-Substituted Spiro Systems by Thermal Rearrangement", Chem. Eur. J. 2014, 20, 1279–1286.

London, G.; von Wantoch Rekowski, M.; Dumele, O.; Schweizer, W. B.; Gisselbrecht, J.-P.; Boudon, C.; Diederich, F. "Pentalenes with Novel Topologies: Exploiting the Cascade Carbopalladation Reaction between Alkynes and Gem-Dibromoolefins", Chem. Sci. 2014, 5, 965-972.

Gawel, P.; Dengiz, C.; Finke, A. D.; Trapp, N.; Boudon, C.; Gisselbrecht, J.-P.; Diederich, F. "Synthesis of Cyano-Substituted Diaryltetracenes from Tetraaryl[3]cumulenes", Angew. Chem. 2014, 126, 4430-4434; Angew. Chem. Int. Ed. 2014, 53, 4341-4345.

Covey, J.; Finke, A. D.; Xu, X.; Wu, W.; Wang, Y.; Diederich, F.; Chen, R. T. "All-optical switching with 1-ps response time in a DDMEBT enabled silicon grating coupler/resonator hybrid device", Opt. Express, 2014, 22, 24530-24544.

Finke, A. D.; Diederich, F. "6,6-Dicyanopentafulvenes: Teaching an Old Dog New Tricks", Chem. Rec. 2015, 15, 19-30.

Dengiz, C.; Breiten, B.; Gisselbrecht, J.-P.; Boudon, C.; Trapp, N.; Schweizer, W. B.; Diederich, F. "Synthesis and Opto-Electronic Properties of Janus-Dendrimer-Type Multivalent Donor-Acceptor Systems", J. Org. Chem. 2015, 80, 882-896.

Gawel, P.; Wu, Y.-L.; Finke, A. D.; Trapp, N.; Zalibera, M.; Boudon, C.; Gisselbrecht, J.-P.; Schweizer, W. B.; Gescheidt, G.; Diederich; F. "Push-Pull Buta-1,2,3-trienes: Exceptionally Low Rotational Barriers of Cumulenic C=C Bonds and Proacetylenic Reactivity", Chem. Eur. J. 2015, 21, 6215-6225.

Beels, M. T.; Biaggio, I.; Reekie, T.; Chiu, M.; Diederich, F. “Highly effcient two-photon absorption and spectroscopy of the first two-photon transition in small donor-acceptor substituted organic molecules“, Phys. Rev. A. 2015, 91, 042818.

Chiu, M.; Tchitchanov, B.; Zimmerli, D.; Sanhueza, I. A.; Schoenebeck, F.; Trapp, N.; Schweizer, W. B.; Diederich, F, ”Strain-Accelerated Formation of Chiral, Optically Active Buta-1,3-dienes“, Angew. Chemie 2015, 127, 356-361; Angew. Chem. Int. Ed. 2015, 54, 349-354.

Cao, J.; London, G.; Dumele, O.; von Wantoch Rekowski, M.; Trapp, N.;  Ruhlmann, L.; Boudon, C.; Stanger, A.; Diederich, F. "The Impact of Antiaromatic Subunits in [4n+2]-pi-Systems:  Bispentalenes with [4n+2] pi-Electron Perimeters but Antiaromatic Character", J. Am. Chem. Soc. 2015, 137, 7178-7188.

Margulies, E. A.; Wu Y.-L.; Gawel, P.; Miller, S. A.; Shoer, L. E.; Schaller, R. D.; Diederich, F.; Wasielewski, M. R. "Sub-Picosecond Singlet Exciton Fission in Cyano-Substituted Diaryltetracenes", Angew. Chem. 2015, 127, 8803-8807; Angew. Chem. Int. Ed. 2015, 54, 8679-8683.

Donckele, E. J.; Finke, A. D.; Ruhlmann, L.; Boudon, C.; Trapp, N.; Diederich, F. "The [2+2] Cycloaddition-Retroelectrocyclization and [4+2] Hetero-Diels-Alder Reations of 2-(Dicyanomethylene)indan-1,3-dione (DCID) with Electron-Rich Alkynes: Influence of Lewis Acids on Reactivity", Org. Lett. 2015, 17, 3506-3509.

Reekie, R. A.; Donckele, E. J.; Ruhlmann, L.; Boudon, C.; Trapp, N.; Diederich, F. "Ester-Substituted Electron-Poor Alkenes for the Cycloaddition–Retroelectrocyclization (CA–RE) and Related Reactions", Eur. J. Org. Chem. 2015, 7264-7275.

Donckele, E. J.; Reekie, T. A.; Trapp, N.; Diederich, F. "Penta-2,4-dien-1-ones by Formal [3+2] Cycloaddition/Rearrangement of Electron-Deficient Diethyl 2-(dicyanomethylene)malonate with Alkynes", Eur. J. Org. Chem. 2016, 714-726.

Dengiz, C.; Prange, C.; Gawel, P.; Trapp, N.; Ruhlmann, L.; Boudon, C.; Diederich, F. "Push-Pull Chromophores by Reaction of 2,3,5,6-Tetrahalo-1,4-benzoquinones with 4-(N,N-Dialkylanilino)acetylenes", Tetrahedron, 2016, 72, 1213-1224.

Reekie, T. A.; Donckele, E. J.; Manenti, G.; Püntener, S.; Trapp, N.; Diederich, F. "A Short Synthesis of Tetrasubstituted NH-Pyrroles", Org. Lett. 2016, 18, 2252-2255.

Gawel, P.; Halabi, E. A.; Schweinfurth, D.; Trapp, N.; Ruhlmann, L.; Boudon, C.; Diederich, F. "Synthesis of Dicyano-Substituted Benzo[c]fluorenes from Tetraaryl[3]cumulenes", Eur. J. Org. Chem. 2016, 2919-2924.

Jayamurugan, G.; Gowri, V.; Hernandez, D.; Martin, S.; González-Orive, A.; Dengiz, C.; Dumele, O.; Pérez-Murano, F.; Gisselbrecht, J.-P.; Boudon, C.; Schweizer, W. B.; Breiten, B.; Finke, A. D.; Jeschke, G.; Bernet, B.; Ruhlmann, L.; Cea, P.; Diederich, F. "Design and Synthesis of Aviram-Ratner-Type Dyads and Rectification Studies in Langmuir-Blodgett (LB) Films", Chem. Eur. J. 2016, 22, 10539-10547.

Reekie, T. A.; Sekita, M.; Urner, L. M.; Bauroth, S.; Ruhlmann, L.; Gisselbrecht, J.-P.; Boudon, C.; Trapp, N.; Clark, T.; Guldi, D. M. Diederich, F. "Porphyrin Donor and Tunable Push-Pull Acceptor Conjugates – Experimental Investigation of Marcus Theory", Chem. Eur. J. 2017, DOI: 10.1002/chem.201700043.

Reekie, T. A.; Gisselbrecht, J.-P.; Boudon, C.; Diederich, F. "Metal-Acetylide Addition to Tetracyanoethylene", Tetrahedron Lett. 2017, 58, 2414-2416.