Guillaume Dunet

 

Postdoctoral Fellow

Location:

HCI G-312

Phone:

+41-44-633 4169

e-mail:

Guillaume Dunet

Education

2000-2004:

Study of Chemistry at the Ecole Nationale Superieure de Chimie de Mulhouse, France

2003:

One-year Industrial Placement at GlaxoSmithKline, Stevenage, UK

2004:

Six-month placement at Actelion Pharmaceuticals, Allschwil, Switzerland

2004:

Ingenieur Chimiste ENSCMu, Master in Organic Chemistry

2004-2007:

Ph.D thesis at the Ludwig-Maximilians Universität München under the supervision of Prof. Paul Knochel

since 2008:

Postdoctoral Fellow at the ETH Zurich in Prof. François Diederich’s group

Halogen Bondings

Halogen bonding is a noncovalent interaction between halogen atoms and a Lewis base. This interaction can be explained by the presence of a so-called σ-hole, a region a positive electrostatic potential situated on the outermost portions of some covalently-bonded halogen atoms. The strength of this interaction decreases in the order I > Br > Cl.

Publications

G. Dunet, P. Knochel, Synlett 2006, 3, 407. Iron-Catalyzed Cross-Coupling between Alkenyl and Dienyl Sulfonates and Functionalized Arylcopper Reagents.

O. Corminboeuf, G. Dunet, M. Hafsi, J. Grimont, C. Grisostomi, S. Meyer, C. Binkert, D. Bur, A. Jones, L. Prade, R. Brun, C. Boss, Bioorg. Med. Chem. Lett. 2006, 16, 6194. Inhibitors of Plasmepsine II : Potential Antimalarial Agents.

G. Dunet, P. Knochel, Synlett 2007, 9, 1383. Highly Stereoselective Cobalt-Catalyzed Allylation of Functionalized Diarylzinc Reagents.

H. Ren, G. Dunet, P. Mayer, P. Knochel, J. Am. Chem. Soc. 2007, 129, 5376. Highly Diastereoselective synthesis of Homoallylic Alcohols Bearing Adjacent Quaternary Centers Using Substituted Allylic Zinc Reagents.

G. Dunet, P. Mayer, P. Knochel, Org. Lett. 2008, 10, 117. Highly Diastereoselective Addition of Cinnamylzinc Derivatives to a-Chiral Carbonyl Compounds.

Last update: Feb. 2008