Brian Frank

 

PhD Student

Location:

HCI G-304

Phone:

+41-44-633 4172

e-mail:

Brian Frank

Education

1999-2004:

Study of chemistry at ETH Zurich

2002:

ERASMUS-SOCRATES exchange semester at Universitat de Barcelona

2003-2004:

Diploma thesis with Prof. F. Diederich at ETH Zurich

2004:

Internship at Hoffmann-La Roche in Basel

since 2005:

PhD with Prof. F. Diederich at ETH Zurich

New organic donor-acceptor molecules with a wide range of potential applications

Fully conjugated donor-acceptor substituted organic molecules are known as promising candidates for future applications in all-optical signal processing, frequency conversion (NLO chromophores), and ultrafast electrooptics. For the fabrication of practical electrooptic devices, critical material requirements, such as large E-O coefficients, high stability, and low optical loss, need to be simultaneously optimized. In the Diederich group di- and tetraethynylethenes (DEEs, TEEs) 1 , donor-substituted cyanoethynylethenes (CEEs) 2 , and, recently, donor-substituted 1,1,4,4-tetracynobuta-1,3-dienes (TCBDs) 3 have been synthesized. The electronic absorption, redox and NLO properties of these compounds have been studied.

The goal of this project is to prepare and characterize new donor-substituted TCBD derivatives.

Publications

S. Sahli, B. Frank, W. B. Schweizer, F. Diederich, D. Blum-Kaelin, J. D. Aebi, H.-J. Böhm, C. Oefner, G. E. Dale, Helv. Chim. Acta. 2005, 88, 731-750. Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-ray Crystal Structure Analysis.

T. Michinobu, C. Boudon, J. P. Gisselbrecht, P. Seiler, B. Frank, N. N. P. Moonen, M. Gross, F. Diederich, Chem. Eur. J 2006, 12, 1889-1905 Donor-substituted 1,1,4,4-tetracyanobutadienes (TCBDs): New chromophores with efficient intramolecular charge-transfer interactions by atom-economic synthesis.

last update: Mai 2006