Haraldur Gardarsson

 

PhD Student

Location:

HCI G-324

Phone:

+41-44-633 4171

e-mail:

Haraldur Gardarsson

Education

2004-2007:

BSc Study in Biochemistry, University of Iceland.

2007:

BSc Thesis with Prof. S. Th. Sigurdsson, University of Iceland.

2007-2009:

MSc Study in Chemistry, University of Iceland.

2009:

Master Thesis with Prof. S. Th. Sigurdsson, University of Iceland.

2009-2010:

Research assistant, Science Institute, University of Iceland.

since 2010:

Graduate Student with F. Diederich, ETH Zurich.

Edge-to-face π---π Interactions


As Edge-to-face aromatic interactions have been invoked to explain the stability of certain protein folding motifs, it is of interest to investigate and quantify the electrostatic component of these interactions. To this end, the Wilcox torsional balance will serve as a scaffold, as it places two aromatic rings in close proximity, orthogonally. New molecular torsional balances will also be pursued, to elucidate the magnitude of various other non-covalent π-interactions, such as sulphur-π and halogen-π.

Publications

H. Gardarsson, S. Th. Sigurdsson, Bioorg. Med. Chem. 2010, 18, 6121-6126. Large flanking sequence effects in single nucleotide mismatch detection using fluorescent nucleoside Çf.

H. Gardarsson, A. S. Kale, S. Th. Sigurdsson, submitted. Structure-function relationships of phenoxazine nucleosides for identification of mismatches in duplex DNA by fluorescence spectroscopy.

Last update: Nov. 2010