Adam Lacy

 

Postdoctoral Fellow

Location:

HCI G-314

Phone:

+41-1-6324-474

e-mail:

Adam Lacy

Education

2003-2007:

MChem in Organic Chemistry, Department of Chemistry, University of Oxford. Final Year Project Supervisor: Prof. Timothy Donohoe.

2007-2011:

D.Phil in Organic Chemistry, Department of Chemistry, University of Oxford. Supervisor: Prof. Timothy Donohoe.

2011-present:

Post-doctoral research, ETH-Zurich. Advisor: Prof. F. Diederich.

Expanding the Chemical Space; Towards Novel Reactions of Alleno-Acetylenes

The 1,3-di-tert-butyl-1,3-diethynylallene (DEA) moiety has found extensive application as a building block in the construction of three-dimensional chiral carbon-rich structures. More recently, it has been discovered that the allene core of these molecules can participate in a wide range of novel reactions to rapidly deliver highly complex molecules with excellent regio-, chemo-, and stereoselectivity. The aim of this project is to expand the number, complexity, and ease of functionalisation of scaffolds that can be accessed from the DEA motif, with a particular focus on the selective formation of derivatives bearing Donor-Acceptor-Substituted Chromophores.

Publications

Donohoe, T. J., Fishlock, L. P., Lacy, A. R., Procopiou, P. A., Org. Lett. 2007, 9, 953–956.

Donohoe, T. J., Kershaw, N. M., Orr, A. J., Wheelhouse, K. M. P., Fishlock, L. P., Lacy, A. R., Bingham, M., Procopiou, P. A., Tetrahedron 2008, 64, 809–820.

Donohoe, T. J., Callens, C. K. A., Flores, A., Lacy, A. R., Rathi, A. H., Chem. Eur. J. 2010, 17, 58–76.

Donohoe, T. J., Lacy, A. R.; Rathi, A. H., Walter, D. S., Chem. Asian J. 2011, 6, 3214–3222.

Donohoe, T. J., Callens, C. K. A., Lacy, A. R., Winter, C., Eur. J. Org. Chem. 2012, 655–663.

Last update: Aug. 2012