Igor Pochorovski

 

PhD Student

Location:

HCI G-320

Phone:

+41-44-632 2955

e-mail:

Igor Pochorovski

Education

2005-2008:

Bachelor studies in Chemistry and Biochemistry at LMU Munich. Bachelor Thesis with Prof. S. Sieber

2006:

Internship at Roche, Penzberg

2007:

Internship at F. Hoffmann-La Roche, Basel

2008:

Visiting researcher at UC Berkeley with Prof. F. D. Toste

2008-2010:

Master studies in Chemistry at ETH Zurich. Master thesis with Prof. F. Diederich

2010:

Internship at Merck, Darmstadt

since 2010:

PhD studies with Prof. F. Diederich at ETH Zurich

 

Electrochemicaly Switchable Resorcin[4]arene Cavitands

Quinoxaline-bridged resorcin[4]arene cavitands have the ability to undergo a triggered conformational transition from a contracted, vase state, to an open, kite state. Three types of stimuli were shown to induce the conformational change: temperature, pH and ZnII ion concentration. The precisely defined conformational change that these types of cavitands undergo makes them ideal for use as switches, receptors, or molecular grippers. However, to parlay the dynamic behavior of the cavitands into such advanced materials, it is important to create cavitands with more practical switching modes. In this regard, cavitands, which would be switchable by electrochemistry, are of particular interest. We will design and synthesize such systems and apply them in the area of nanorobotics, as molecular grippers. 

Publications

I. Pochorovski, B. Breiten, W. B. Schweizer, F. Diederich, Chem. Eur. J. 2010, 16, 12590-12602. FRET Studies on a Series of BODIPY-Dye-Labeled Switchable Resorcin[4]arene Cavitands. 

I. Pochorovski, F. Diederich, Chem. Isr. J. 2012, 52, 20-29. Fluorophore-Functionalized and Top-Covered Resorcin[4]arene Cavitands.

I. Pochorovski, C. Boudon, J.-P. Gisselbrecht, M.-O. Ebert, W. B. Schweizer, F. Diederich, Angew. Chem. Int. Ed. 2012, 51, 262-266. Quinone-Based, Redox-Active Resorcin[4]arene Cavitands.

I. Pochorovski, M.-O. Ebert, C. Boudon, J.-P. Gisselbrecht, W. B. Schweizer, F. Diederich, J. Am. Chem. Soc. 2012, 10.1021/ja306473x. Redox-Switchable Resorcin[4]arene Cavitands: Molecular Grippers.

Last update: September 2012