Tatsuya Yamaguchi

 

Postdoctoral Fellow

Location:

HCI G-306

Phone:

+41-44-632 2912

e-mail:

  Tatsuya Yamaguchi

Education

1995-1999:

BS degree, Department of Biomolecular Science, Faculty of Science, Toho University

1999-2001:

MS degree, Department of Biotechnology, Graduate School of Engineering, The University of Tokyo

2001-2004:

Ph. D, Department of Biotechnology, Graduate School of Engineering, The University of Tokyo

2004-2005:

Aida Nanospace Project ERATO, JST

2004-present:

Postdoc with Prof. F. Diederich at ETH Zurich

Dendritic biosensors

Biosensors are fine tools to develop new drugs. Here we propose novel biosensors where dendritic molecules bearing ligands are adsorbed on the cationic surface via ionic interaction. The dendritic structure would provide larger number of binding sites and show high sensitivity as biosensors compared with previous examples. Firstly we are investigating binding properties ofb-lactamase between the ligands on the dendritic molecules.

Publications

T. Yamaguchi, T. Kimura, H. Matsuda, and T. Aida, Angew. Chem. Int. Ed. 2004, 43, 6350-6355 (Highlighted as a VIP paper) Macroscopic Spinning ChiralityMemorized in Spin-Coated Films of Spatially Designed Dendritic Zinc Porphyrin J-Aggregates.

T. Yamaguchi, N. Ishii, K. Tashiro, and T. Aida, J. Am. Chem. Soc. 2003, 125, 13934-13935. (Science 2003, 302, 1297: Editor's Choice) Supramolecular Peapods Composed of a Metalloporphyrin Nanotube and Fullerenes.

T. Ikeue, Y. Ohgo, T. Yamaguchi, M. Takahashi, M. Takeda, and M. Nakamura, Angew. Chem., Int. Ed. 2001, 40, 2617-2620. Saddle-Shaped Six-Coordinate Iron(III) Porphyrin Complexes Showing a Novel Spin Crossover between S= 1/2 and S= 3/2 Spin States.

T. Ikeue, Y. Ohgo, T. Saitoh, T. Yamaguchi, and M. Nakamura, Inorg. Chem. 2001, 40, 3423-3434. Factors Affecting the Electronic Ground State of Low-Spin Iron(III) Porphyrin Complexes.

T. Ikeue, T. Yamaguchi, Y. Ohgo, and M. Nakamura, Chem. Lett. 2000, 342-343. Direct Observation of Conformers Caused by the Difference in Ligand Orientation in Low Spin Iron(III) Porphyrin Complex.

T. Ikeue, T. Saitoh, T. Yamaguchi, Y. Ohgo, M. Nakamura, M. Takahashi, and M. Takeda, Chem. Commun. 2000, 1989-1990. Formation of Pure Intermediate Spin Complexes in Highly Nonplanar Iron(III) Porphyrins.

M. Nakamura, T. Yamaguchi, and Y. Ohgo, Inorg. Chem. 1999, 38, 3126-3131. Barriers to Inversion of Nonplanar Ferric Porphyrin Radical Cation: Comparison with the Corresponding Neutral Complexes.